Why Should You Choose Liposomal Creams?

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With so many skincare products available on the market today, it can be overwhelming to select the best option for your unique skin type. Given that so many topical formulas contain abrasive chemicals, finding a potent natural formula is like blindly grabbing a needle from a haystack. With the advent of new technologies in skincare, liposomal creams have become the most efficient method for delivering the highest concentration of ingredients to skin cells.

What makes liposomal creams superior to competitors? It all has to do with the amazing capabilities of liposomes, protective “bubbles” that bring ingredients to designated areas throughout the body. Below, we take a closer look at what liposomes are and why you should choose liposomal creams for daily skin nourishment.



Used widely throughout the pharmaceutical industry and increasingly in supplemental formulations, liposomes are changing the way ingredients are transported within the body. Liposomes are unique phospholipid structures which are manually agitated into forming a structurally supportive vesicle. Comprised of at least one lipid bilayer, they encapsulate active ingredients, nutrients, drugs, etc., and bring them safely past intestinal membranes to targeted tissues.

Where liposomes have an edge over other methods is their ability to increase bioavailability of active ingredients. In non-liposomal formulas, nutrients are partly destroyed by digestive enzymes, failing to reach the cells or blood vessels in their full form. Liposomal supplements, however keep ingredients preserved until they are ready to be used.


When choosing a product, most consumers want assurance that what they are paying for is worth the price. Regarding liposomal creams, we list the top reasons for choosing this formula over others. You may be surprised just how much liposomal creams can make a difference in your skincare regimen.


Whether you are looking for a formula to nurture the skin daily or a solution to various irritating skin conditions, liposomal creams offer the most potential for success. Liposomes allow active ingredients to penetrate into deeper layers of the epidermis than other methods. Liposomes maximise the bioavailability of skin-soothing nutrients to affected cells and traps in moisture to keep your skin feeling fresh and healthy.

Ginger with cream on face

A recent study was conducted to assess the therapeutic effects of a liposomal formulation of tranexamic acid versus hydroquinone on melasma. Melasma is a tan or brown discoloration on the skin which can potentially be reduced by said formulas. The trial used a split-face technique to gauge the different outcomes of each cream on the condition. The resulting MASI scores (Melasma Area and Severity Index) indicated that the liposomal formulation indeed showed a greater decrease than its opponent.


Due to the protective nature of the liposome, liposomal creams contribute to slower metabolisation of nutrients in the blood stream. This in turn allows the active ingredients to sustain a longer course of benefits for the consumer. Liposomes are amphiphatic structures, meaning they contain a hydrophilic (water-attracting) head and a hydrophobic (water-repelling) tail. This results in a secure structure which protects ingredients until they are ready to be used. When that point arrives, the liposome releases the maximum amount of nutrients to its target destination.


One of the greatest upswings to creams developed with liposomes is their biocompatible nature. Liposomes have a very low toxicity level and sustain no adverse effects on the body. As an all-natural method of transportation, liposomes are efficient as a biodegradable form of protection for contents within.

Although liposomes originate as phospholipids, they must be manually prepared in order to be used in liposomal creams. This is carried out most often under the process of extrusion, which results in the formation of secure vesicles. Extrusion techniques vary, but the general concept involves forcing liposomes through a series of filters to obtain a unanimous diameter and structure. Liposomes made under the process of sonication (applying ultrasonic frequencies) will not be as secure as those prepared through extrusion.


A financial benefit to choosing liposomal creams is the decreased amount needed to obtain the product's full effects. Since liposomes can dramatically increase bioavailability of active ingredients in skin creams, you may be able to reduce your usage to smaller applications while getting the same benefits as a heavy doseof a non-liposomal cream. In the long run, liposomal creams can help save you some money on skincare and perhaps even reduce your daily usage.

Liposome explanation


Cibdol now offers four potent liposomal CBD creams which are packed with all-natural skin-nurturing ingredients. Aczedol, Hydradol, Soridol and Zemadol all contain a liposomal formulation to bring active ingredient CBD deep into layers of the skin. CBD has been shown to encourage anti-inflammatory and anti-bacterial functions as well as encourage proper cell proliferation and differentiation. When optimised with liposomes, CBD is delivered in higher concentrations than ever before with a potent dose of all-natural nourishment.

When developing new technologies for Cibdol CBD supplements, liposomes asserted themselves as an ideal formulation for providing a rigorous course of natural skin rejuvenation. For sufferers of various skin conditions, Cibdol’s new CBD creams are specially formulated to bring intensive hydration to damaged skin cells, while mediating the skin's inflammatory response.

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